(2017). Further, noted herbalist Maria Nol Groves, mentions magnolia bark as a helpful herb for reducing nighttime sleep disturbances. Magnolol was also able to reduce the time it took for mice to fall asleep. As far back as the 7th century, Magnolias were cultivated in the gardens of Chinese Buddhist temples. Beach Animal Rehabilitation Center (BARC) is a one of a kind veterinary clinic, serving Los Angeles and Orange Counties, specializing in rehabilitation for dogs and cats. If cancer is smart, we have to be brilliant and with leading-edge integrative strategies, we can be. Exercise also helps regulate your bodys stress responses so you become less reactive when faced with stressors. https://doi.org/10.1093/jpp/rgab067, Chen, C. R., Zhou, X. The supplement can be found at many online and retail stores. Healthy eating: When youre feeling stressed, your instinct may be to grab for sweet, salty, fatty foods but those can add to your bodys stress load. Some researchers believe that these effects are due to honokiol, a natural compound in the bark. Clinical studies will be required to determine whether it is safe or effective for any purpose. Garrison, R., & Chambliss, W. G. (2006). Magnolia bark is considered a safe supplement for human consumption. https://doi.org/10.1016/j.neuropharm.2012.06.031. When taken together, the evidence conveys that magnolia bark extract may help with the psycho-affective symptoms of menopause. And while stress is unavoidable now more than ever you can take steps to help your body respond in a healthier way. This study also supports previous research showing that regular meditation reduces other pro-cancer proteins like TNF-alpha and CRP these inflammatory markers are triggered by the master regulator, galectin-3. Excess stress is a common problem. Here are 15 herbs with powerful antiviral properties. This item: Swanson Magnolia Bark Antioxidant Support 400 Milligrams 60 Capsules. Anxiety is a mental health disorder that affects mood and behavior and is often brought on by increased stress. The magnolia tree has long glossy leaves and blooms from April to June. Magnolia bark is a powerful supplement prepared from the bark, leaves, and flowers of the houpo magnolia tree. Kuribara, H., Stavinoha, W. B., & Maruyama, Y. Anticancer research, 30(3), 777783. Stress can have a whirlwind effect on your emotions. The researchers found that the isoflavones effectively lessened the severity of classic menopausal symptoms, including hot flashes, while magnolia bark eased the participants anxiety. Some researchers believe that these effects are due to honokiol, a natural compound in the bark. Here is a closer look at some of the potential benefits of magnolia bark. Researchers ensured that there was a steady dose of honokiol throughout the study (while the other ingredients varied) in order to confirm their hypothesis. I discussed your question with Tieraona Low Dog M.D.,an internationally recognized expert in the fields of integrative medicine, dietary supplements and womens health,and an expert on botanical medicine. Taking even 10 minutes in nature can lift your mood and reduce your stress level. See additional information. It is also commonly used to support gastrointestinal health. Is Garcinia Cambogia Safe for Weight Loss? Note that the numbers in parentheses (1, 2, etc.) Grieve, M. (1931). A similar study in more than 600 menopausal women found that consuming a magnolia bark supplement daily for 12 weeks relieved symptoms of insomnia, irritability, and anxiety (32). Research on honokiol has found that it can reduce inflammation in the brain and spinal cord specifically, partly due to its ability to cross the blood-brain barrier (14). Dietary Supplementation With Magnolia Bark Extract Alters Chicken Intestinal Metabolite Levels. White oak bark, scientifically known as Quercus alba, translates to "fine tree." Historically used to remedy a long list of conditions, this ingredient is mainly added to washes, baths, teas, tinctures, and other infusions. The bark of the magnolia . It can grow at an additional height of 24 inches per year. Based on extensive research and decades of clinical experience, Ive found that targeting galectin-3 allows us to address a key cause of cancer development and progression, supporting and enhancing the bodys ability to overcome the disease. Additionally, the magnolol appeared to increase the number of times the mice woke up during sleep but decrease the length of time they were awake. Hospital affiliations include Hoag Memorial Hospital Presbyterian. Honokiol promotes non-rapid eye movement sleep via the benzodiazepine site of the GABA(A) receptor in mice. Furthermore, its best to speak with your healthcare provider before taking magnolia bark supplements, especially if youre currently using other supplements or medications. A 24-week study in 89 menopausal women experiencing symptoms of sleep and mood alterations were given a supplement containing 60 mg of magnolia bark extract and 50 mg of magnesium daily. Effect of Magnolia officinalis and Phellodendron amurense (Relora) on cortisol and psychological mood state in moderately stressed subjects. Those gentle detox abilities make it easier for your body to cope with other challenges, including chronic stress. Many benefits of magnolia bark can be attributed to two powerful polyphenols magnolol and honokiol. Isaac Eliaz, MD, MS, LAc has been a recognized expert in the field of integrative medicine since the early 1980s, with a specific focus on cancer, immune health, detoxification and mind-body medicine. Biological activity and toxicity of the Chinese herb Magnolia officinalis Rehder & E. Wilson (Houpo) and its constituents. Cissus quadrangularis: Uses, Benefits, Side Effects, and Dosage, Galangal Root: Benefits, Uses, and Side Effects. Amid the constant barrage of stressors environmental toxins, destructive emotions, fast-paced lifestyles we have to find a way to turn off the biochemical alarm thats constantly triggering our fight or flight responses. There are so many ways that chronic stress harms your body, mind, and mood. Experimental & molecular medicine, 40(6), 617628. It produces mature red, conelike fruit from September through October when it opens up to display its seeds. Magnolia bark for anxiety. As mentioned, magnolia bark extract appears to have protective effects against many neurological conditions. That helps your body better adapt to rapidly changing situations and shut down stress responses more easily. The bark then undergoes a process of drying and boiling before its infused into a tincture for oral consumption. The women experienced significant improvements in insomnia, anxiety, mood, and irritability (31). The bark is harvested from April to June where it is then dried in shade. Here are some notable sorrel. Magnolia bark I tried 5 ish times desperate for it to work and it was a pretty nightmarish experience every time. Here are common signs of too much stress. Researchers believe magnolia barks ability to activate specific proteins was responsible for the anti-cancer effects. Z., Luo, Y. J., Huang, Z. L., Urade, Y., & Qu, W. M. (2012). are clickable links to these studies. There are many potential health benefits of magnolia bark offered by two key micronutrients magnolol and honokiol present in it. And part of that means better understanding galectin-3. In a clinical trial involving healthy, overweight, premenopausal women, Magnolia officinalis extract (MOE) demonstrated a weight loss effect on those that overate when they were stressed. In this article, we will look at the health benefits of magnolia bark, its safety, and its history. Oxidative stress also appears to play a significant role in many changes in the body and mind that accompany aging (11). Magnolia officinalis, also known as magnolia bark, has been widely used in traditional Chinese medicine and has many benefits. Amazon.com: LES Labs Cortisol Health - Stress Relief, Balanced Cortisol Response, Relaxation & Deep Sleep - Phosphatidylserine, Magnesium, Magnolia Bark, Rhodiola Rosea & Ashwagandha - 60 Capsules : Health & Household Constant stress knocks your whole body off-track, causing physical, mental, and emotional distress. A second study in mice observed similar outcomes after administering honokiol, which also decreased the amount of time it took the mice to fall asleep and transition into non-REM sleep (28). This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. Nutrition journal, 7, 11. https://doi.org/10.1186/1475-2891-7-11. Cancer statistics, 2020. Magnolia bark has a sedative effect on the body and has been used to promote sleep and ease anxiety. Futurebiotics Ashwagandha Capsules Extra Strength 3000mg - Stress Relief Formula, Natural Mood Support, Stress, Focus, and Energy . Honokiol, a natural biphenyl, inhibits in vitro and in vivo growth of breast cancer through induction of apoptosis and cell cycle arrest. Terms and Conditions That can lock you in a never-ending stress cycle and likely searching for natural ways to relieve stress. Suma Root: Nutrients, Benefits, Downsides, and More, Sorrel: Nutrients, Benefits, Downsides, and Recipes, 15 Impressive Herbs with Antiviral Activity, Anti-Inflammatory Diet 101: How to Reduce Inflammation Naturally, 13 of the Most Anti-Inflammatory Foods You Can Eat, The Signs and Symptoms of Too Much Stress. Currently, magnolia bark is widely used in food supplements and beauty products.You can also find the bark's name listed in the American Pharmacopeia as a bitter antimalarial tonic. Again, note that magnolia bark extract was not the only supplement given in this study. https://doi.org/10.1021/np800494e, Siegel, R. L., Miller, K. D., & Jemal, A. Science. Magnolia bark is a popular herb used for gut health and stress-induced anxiety. The Extraordinary Importance of Sleep: The Detrimental Effects of Inadequate Sleep on Health and Public Safety Drive an Explosion of Sleep Research. Magnolol exerts anticancer activity in hepatocellular carcinoma cells through regulating endoplasmic reticulum stress-mediated apoptotic signaling. Our team includes licensed nutritionists and dietitians, certified health education specialists, as well as certified strength and conditioning specialists, personal trainers and corrective exercise specialists. Retrieved from: https://www.christopherhobbs.com/webdocs/class-handouts/various/Healing-Sleep-Breitenbush.pdf, Hu, J., Chen, L. J., Liu, L., Chen, X., Chen, P. L., Yang, G., Hou, W. L., Tang, M. H., Zhang, F., Wang, X. H., Zhao, X., & Wei, Y. Q. His therapy, or "thorapy" as The REAL Bark team calls it . The blend also improved the mood of the participants receiving the supplement. Exercising leads to the release of endorphins, natural feel-good chemicals that combat the effects of stress. Journal of natural products, 72(1), 168171. Neuropharmacology, 63(6), 11911199. This article reviews what it is, its best uses, potential benefits, and side, Suma root has many medicinal uses in folk medicine, but scientific evidence supporting its purported benefits is lacking. Get it as soon as Wednesday, Apr 19. You also agree to receive emails from DrWeil.com, and you may opt Read on for proven tactics. Depression and anxiety. P & T : a peer-reviewed journal for formulary management, 43(12), 758763. 2023 Healthline Media LLC. Other powerful herbs found in stress preparations and on their own in tea and/or supplement form are lemon balm, valerian, California poppy, hops, milky oats, St. Johns Wort, skullcap, and . Later, it was described in many famous Chinese medical texts such as the "Jingui Yaolue" and the "Shanghan Lun" (ca. Note that the numbers in parentheses (1, 2, etc.) Neolignans are a type of polyphenol micronutrient in plants. When cortisol levels decrease, it suggests that overall stress has also decreased. Getting adequate amounts of deep sleep is key for mental and physical health. Retrieved from: https://static1.squarespace.com/static/55636a78e4b0658666cb6541/t/5eac6913be207478cdbd2980/1588357463831/Perky+Calm+Alert+Slides.pdf, Ogobuiro I, Gonzales J, Tuma F. (2021) Physiology, Gastrointestinal. In fact, eye-opening research shows a direct link between galectin-3 and depression, making this alarm protein a strong potential target in treating stress-related mental illness. In a recent animal study, Magnolia officinalis extract improved and normalized levels of gut bacteria in mice. Magnolia bark continues to be used in dietary supplements today, marketed for potential benefits like reducing stress, decreasing inflammation, and as a natural sleep aid. Luckily, a large and fast-growing body of research has given us a specific therapeutic target to achieve this goal: the biological protein galectin-3. Over-the-Counter Sleep Aids Overview Magnolia (Magnolia biondii) is a plant found in parts of Asia and North and South America. No adverse effects related to magnolia bark or the compounds it contains have been observed. Honokiol was found to reduce anxiety levels in the mice without slowing down motor functions. All Rights Reserved. A modern herbal. The Tabebuia tree's bark is highly resistant to rotting, mold, and other common tree pathogens (bacteria, viruses, or other tiny organisms that may cause disease). biloba fruits and their protective effects against free radical-induced oxidative damage. The Physiomedical Dispensatory. Our team aims to be not only thorough with its research, but also objective and unbiased. Magnolia bark is a popular herb in traditional Chinese and Japanese medicine. Nature: Spending time outdoors in nature helps your body and mind relax. Zhang, W. W., Li, Y., Wang, X. Q., Tian, F., Cao, H., Wang, M. W., & Sun, Q. S. (2005). Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. 2005 - 2023 WebMD LLC, an Internet Brands company. One possible concern is its potential to interact with other supplements or medications. It takes elements of our Lemon Balm extracts, and pushes the effects a little bit deeper. When alarm protein galectin-3 gets activated in response to stress, it kicks off a series of inflammatory reactions. Our website services, content, and products are for informational purposes only. The tree was later transported and cultivated in England. This dried bark known for its sharp smell and bitter taste is then soaked in a traditional medicine tincture for oral use. (2018). And since stress triggers galectin-3, the alarm protein, it also sets off inflammation even in your brain. This tree belongs to the Magnoliaceae family and can grow to a mature height from 16 ft up to 80 ft. You can easily identify the magnolia tree from its large and fragrant flowers that often reach 8 inches in diameter. Once it matures, the height can reach up to 100 feet and the canopy can spread at up to 70 feet. Last medically reviewed on April 7, 2020, Cissus quadrangularis is a plant that has long been used as a natural remedy to treat a wide variety of ailments. The benefits of magnolia bark have been shown to help support weight loss through stress reduction and management. The genus of the tree was named after the French physician, Pierre Magnol, who was a well-regarded botanist in the 17th century. The Best Supplements for Healthy Digestion, How to Get the Protective Power of Vitamin K, Anti-inflammatory: able to reduce inflammation in the body, Antimicrobial: able to kill or slow the spread of bacteria, viruses, and fungi, Antioxidant: able to protect cells against damage by free radicals, Neuroprotective: able to protect brain cells against damage, Antidiabetic: able to control blood sugar and prevent diabetes, Antidepressant: able to reduce the symptoms of depression, Antiangiogenic: able to keep new blood vessels from forming and prevent tumor growth, Banxia Houpo Tang: This Chinese formula is said to move stagnant qi in the solar plexus, head, and throat area., Saiboku-To: This Japanese formula has anti-inflammatory properties that can help to reduce asthma symptoms.. Further, in traditional Chinese medicine, the bark was used for the stomach, large intestines, and lungs. Once their inner surface turns dark brown or purplish brown, the TCM practitioners steam, roll, and dry them. During the 7th century, monks in the Chinese Buddhist temples grew these trees in their gardens for use in treating conditions like depression, asthma, muscle pain, and headache. In an animal trial, researchers used an isolated active constituent of magnolia bark, honokiol, to test its anxiolytic effects on stressed mice. Chronic stress takes a huge toll on your physical health. In another in vitro study, honokiol showed promising effects on oral cancer cells. When the danger passes, the system turns off and resets. Magnolia bark is a popular herb in traditional Chinese and Japanese medicine. Since ancient times, herbs have been used as natural remedies for a variety of viral infections. $7.77 ($0.13/Count) In Stock. Additional therapeutic adjuncts include medicinal mushrooms for broad-spectrum immune support, as well as researched botanical and nutrient formulas with unique anticancer mechanisms. Below are the top researched-backed magnolia bark benefits for health. Cancer acts with innate intelligence, like it has a mind of its own, and uses sophisticated mechanisms to survive at any cost. Honokiol: When stress and anxiety overwhelm your mind and your life, honokiol a compound extracted from magnolia bark offers quick, calming relief. Another in vitro study involving magnolol proved to have similar effects in liver cancer cells. Thus, it cannot be said with certainty that the effects were due solely to the magnolia bark. It is especially effective when paired with ginger. https://doi.org/10.3322/caac.21590, Talbott, S. M., Talbott, J. https://doi.org/10.1111/jcmm.13474, Kalman, D. S., Feldman, S., Feldman, R., Schwartz, H. I., Krieger, D. R., & Garrison, R. (2008). As an integrative MD and researcher, licensed acupuncturist and life-long practitioner of Buddhist meditation, Ive developed a unique perspective and methodology around mind-body medicine, and specifically, our innate abilities to heal ourselves and others. Impacts of gut bacteria on human health and diseases. Effects of magnolol and honokiol derived from traditional Chinese herbal remedies on gastrointestinal movement. | Henriette's Herbal Homepage. They produce aromatic, large, and attractive flowers that sometimes bloom up to 8 inches in diameter. In an 1869 medical text written by Dr. William Cook, he mentions that magnolia bark has relaxing qualities and can be used for someone who has nervous characteristics. Through many of the same mechanisms that it supports sleep by, magnolia bark can help reduce anxiety by activating receptors in the endocannabinoid system (like CBD) and reducing adrenaline and other stress hormones like cortisol. Grandchildren are some of lifes greatest treasures. OncoTargets and therapy, 11, 52195226. Another study using the same magnolia/phellodendron blend found that it reduced anxiety levels in premenopausal female adults. Save my name, email, and website in this browser for the next time I comment. But you can take specific steps to help your mind and body calm down even in the face of non-stop stressors. She has a bachelor of science in communications as well as having completed a post-baccalaureate certificate in herbal studies. All these barks are then stacked up in a wet area. Benefit 5 - Brain Health Healthy sleep is essential for cognitive performance. are clickable links to medically peer-reviewed studies. Along with the bark, sometimes these flowers and leaves are also used for making medicine. And when youre already feeling anxious and worried, the last thing you need is a stressed-out immune system. In a preventative animal study, magnolia barks active constituent, honokiol, was able to prevent the development of skin cancer. It takes an enormous toll on your immune system, leaving you more vulnerable to any infection thats going around. International journal of oncology, 30(6), 15291537. Its one of the top stress relievers out there. Moreover, oxidative stress is widely believed to contribute to diabetes and its related complications. https://doi.org/10.1055/a-0642-1966, Shen, C. C., Ni, C. L., Shen, Y. C., Huang, Y. L., Kuo, C. H., Wu, T. S., & Chen, C. C. (2009). BARC is specifically aimed at helping pets live longer, healthier lives by treating them using a holistic approach combining both Eastern . This is how we can shift out of survival mode, and into a state of health, wellness and longevity. Kuribara, H., Kishi, E., Hattori, N., Okada, M., & Maruyama, Y. B: Biological activity and toxicity of the Chinese herb Magnolia officinalis Rehder & E. Wilson (Houpo) and its constituents., Memorial Sloan Kettering Cancer Center: Magnolia officinalis., Neuropharmacology: Magnolol, a major bioactive constituent of the bark ofMagnolia officinalis, induces sleep via the benzodiazepine site of GABAA receptor in mice., Nutrition Journal: Effect of a proprietary Magnolia and Phellodendron extract on stress levels in healthy women: a pilot, double-blind, placebo-controlled clinical trial., Oxidative Medicine and Cellular Longevity: Oxidative Stress and Inflammation: What Polyphenols Can Do for Us? Plant polyphenols as dietary antioxidants in human health and disease., Planta Medica: Safety and Toxicology of Magnolol and Honokiol., Pharmacological Research: Honokiol for cancer therapeutics: A traditional medicine that can modulate multiple oncogenic targets., The Botanical Institute: 6 Magnolia Bark Benefits: Dosage & Safety., The Journal of Pharmacy and Pharmacology: Honokiol, a putative anxiolytic agent extracted from magnolia bark, has no diazepam-like side-effects in mice., World Journal of Gastroenterology: Effects of magnolol and honokiol derived from traditional Chinese herbal remedies on gastrointestinal movement.. Exercise: Physical activity helps your body blow off steam, but its benefits dont stop there. Research shows that both magnolol and honokiol are, by nature: The extract of the magnolia bark has been used for thousands of years in traditional Chinese and Japanese medicine. We increase our longevity and health-span significantly, by balancing our biochemical alarm system. Anxiety also has a tendency to disrupt gut health. Researchers found that a combination of tumor radiation and honokiol had the capability to reduce a mouse lung tumor by 78%. For mild to moderate depression, I recommend exercise 30 minutes a day. It may also possess anti-cancer effects in higher doses. Stress comes at you all day, from every angle, now more than ever. U.S. STD Cases Increased During COVIDs 2nd Year, Have IBD and Insomnia? Magnolol inhibited cancer growth and reduced tumor size in vitro. One particular extract that exhibits remarkable ability against cancer is pure honokiol, a highly active molecule derived from Magnolia officinalis bark. The Journal of pharmacy and pharmacology, 51(1), 97103. Magnolia bark is the bark of the Magnolia tree which is part of the Magnoliaceae family. At the same time, fascinating research continues to unravel the vast network of mechanisms that connect our mind and emotions to our physical health. https://doi.org/10.1211/0022357001777432, Lloyd & Lloyd (1887). The use of MCP, as well as the application of mind-body exercises, are two proven methods to address unhealthy galectin-3. Although there isnt much historical information on the magnolia tree and magnolia bark in Asia, there were sightings of the tree in North Carolina as early as the 16th century. The same study observed that the same dose increased REM (rapid eye movement) and non-REM sleep. So how exactly do we solve this paradox? It was also valued in TCM for its ability to reduce inflammation, anxiety, and bloating.. Today, you can also find this herb in the medical stores sold as bundles of 4 inches long magnolia bark strips. summary The bark, leaves, and. Meditation: If youve never tried meditation before, you might feel like youre doing it wrong but there is no wrong here. It also helps reduce brain inflammation, which has been closely linked with depression, anxiety, and other mood disorders. Researchers go on to mention that there were no toxic effects associated with honokiol. He is a respected formulator, clinician, researcher, author and educator. Journal of Zhejiang University. Magnolia essential oil is known for stimulating the lymphatic system and helps in making the liver to function properly and help in toxins elimination. It involves focused mindful breathing and spiritual engagement. Modern research shows that magnolia bark has anti-inflammatory, antioxidant, stress, and weight-reducing effects. Grandchildren are some of lifes greatest treasures. Magnesium supplements can also interact with other drugs and change how they work in your body. It stays on ready alert around the clock and never gets to stand down. Honokiol, a putative anxiolytic agent extracted from magnolia bark, has no diazepam-like side-effects in mice. The second formula, called Saiboku-To (Japanese) is a formula that is said to reduce asthma symptoms through its anti-inflammatory properties. Dr. Weil's FREE health living advice delivered to you! 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